Every piece links its primary source at the top and answers one question: what changes for a plant.
Scale-Up & CapacityResearch
We read 46 primary sources. ATF and TFF use the same hollow fibre and differ in the pump. Both hold back product as the filter ages, the head-to-head studies disagree, and what fouls the fibre is particles the size of its pores.
Precision FermentationBrief
Scale-Up & CapacityResearch
Scale-Up & CapacityBrief
91% vs 60%
Cell recovery after 25 days of suspension culture, encapsulated vs non-encapsulated stem-cell-derived islets (bioRxiv preprint)
Bioprocess 4.0Brief
Bioprocess 4.0Brief
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ResearchATF vs TFF in perfusion: what the filter holds back, why it fouls and how it scales
ResearchFed-batch vs perfusion: what the numbers say on output, plant size and costEditorial coverage from primary sources. No company on this list paid to appear. See Interests.
USP and DSP scale-up, new plants, CDMO capacity, reshoring and the policy behind it.
PAT, automation, AI, digital twins, process data and how to validate them.
Industrial scale-up, capacity and economics of precision and biomass fermentation.
Biomanufacturing and pharma manufacturing moves in Spain, Portugal and Italy.