Catalym Raises $150m for Cancer Breakthrough

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💰 German cancer specialist Catalym GmbH has raised $150m to finance proof-of-concept studies.
🔬 The aim is to demonstrate the efficacy, safety, and licensing potential of Visugromab plus Nivolumab in solid tumors.
💉 CatalYm GmbH plans to start Phase IIb trials in 2025.
🧪 Visugromab is a humanized monoclonal antibody designed to neutralize the tumor’s own Growth Differentiation Factor-15 (GDF-15).
💼 The financing round was led by Canaan Partners and Bioqube Ventures, and supported by other investors.
📢 Catalym Raises $150m to Revolutionize Cancer Treatment

Introduction:

German cancer specialist Catalym GmbH has raised US$150m to finance proof-of-concept studies.

Main points:

  1. The funding will be used to expand the development of Visugromab in randomised Phase IIb trials in stratified checkpoint-naïve first- and second-line treatments.
  2. Visugromab is a humanised monoclonal antibody designed to neutralise the tumour’s own Growth Differentiation Factor-15 (GDF-15), which is a key mediator of immune resistance to cancer therapeutics.
  3. The financing round was led by Canaan Partners and Bioqube Ventures and supported by Forbion’s Growth Opportunities Fund, Omega Funds, Gilde Healthcare, and existing investors.
  4. Visugromab has shown anti-tumour activity in combination with checkpoint inhibitors and has induced complete tumour remission in some patients.
  5. The funds will also be used to conduct Phase IIb trials in the indications of NSCLC, UC, HCC, and bladder cancer.

Conclusion:

The funding will enable Catalym to further develop Visugromab and demonstrate its efficacy, safety, and licensing potential in Phase IIb trials. If successful, Visugromab could be a promising treatment option for various types of cancer.

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