Introduction:
DefiniGEN Ltd. and Atelerix Ltd. have collaborated to successfully ship liver models from the UK to the US without freezing them, preventing cell damage and loss of function. This achievement is made possible by combining DefiniGEN’s iPSC hepatocytes with Atelerix’s hydrogel preservation technology.
- Freezing damage and loss of function of cryopreserved cells pose a challenge in organoid cell and cell-based testing of pharmaceuticals.
- Atelerix’s hydrogel preservation technology protects living cells during transport, ensuring stability for at least 3-5 days.
- DefiniGEN’s iPSC hepatocytes are functionally stable for extended periods, making them ideal for drug discovery and toxicology-related research.
- In vitro liver models provide a controlled environment for studying liver functions and diseases, reducing the need for live animal testing.
- The collaboration between DefiniGEN and Atelerix allows for improved functional assays without the reliance on cold chain logistics.
Conclusion:
The collaboration between DefiniGEN and Atelerix has resulted in the successful shipment of liver models without freezing, preserving cell function and preventing damage. This achievement has significant implications for organoid cell and cell-based testing in pharmaceutical research, as well as reducing the reliance on cold chain logistics. In vitro liver models offer a valuable tool for studying liver functions and diseases, leading to the development of safer and more effective medications.
