Introduction:
This article discusses the convergence of two pathways in bioprocessing: the potential use of a bad bacterium for good and the combination of synthetic biology and bioprocessing for improved sustainability. The article highlights the work of Sungho Jang, a synthetic biologist, and his colleagues, who are exploring the use of Vibrio bacteria as a next-generation chassis for synthetic biology.
- Vibrio bacteria, known for causing diseases like cholera, have emerged as promising next-generation chassis for synthetic biology.
- These bacteria have rapid growth rates and versatile substrate utilization, making them well-suited for the design-build-test-learn cycle of synthetic biology.
- Vibrio bacteria possess a higher number of ribosomes compared to Escherichia coli, enabling enhanced synthesis of proteins.
- Further advancements in genome engineering tools for Vibrio bacteria are needed to fully realize their potential as a synthetic biology chassis.
- If new genome engineering tools are developed for Vibrio, it could significantly impact the field of bioprocessing.
Conclusion:
The convergence of pathways in bioprocessing, specifically the use of Vibrio bacteria and synthetic biology, presents exciting possibilities for improving protein production and sustainability. With advancements in genome engineering tools, Vibrio bacteria could become a powerful next-generation chassis for synthetic biology and revolutionize the field of bioprocessing.
