🚀 This technology allows for automated, modular RNA manufacturing.
🌱 It ensures faster market readiness for RNA therapies, such as mRNA and saRNA.
💡 BiaB offers continuous flow production, increasing efficiency and flexibility in RNA drug manufacturing.
📈 Quotient aims to transform RNA drug development and deliver rapid solutions for new therapies.
Introduction:
Quotient Sciences has introduced a significant advancement in RNA production with the installation of Centillion’s Biofoundry-in-a-Box (BiaB™). This state-of-the-art platform aims to streamline the manufacturing of RNA-based therapeutics, including mRNA and self-amplifying RNA, enhancing the efficiency of drug development processes.
- The Biofoundry-in-a-Box (BiaB™) is a modular, integrated GMP platform enabling end-to-end RNA manufacture, designed to accelerate the development of RNA therapies.
- BiaB utilizes a continuous flow-based manufacturing process that allows for higher productivity and flexibility while occupying a smaller physical footprint compared to traditional methods.
- The technology supports the encapsulation of larger quantities of RNA, creating RNA lipoparticles (RNA-LNPs) for both preclinical and clinical evaluations.
- Quotient Sciences aims to manufacture up to one million doses of RNA therapies within a 24-hour timeframe, facilitating rapid response and development of RNA-based products.
- The partnership with Centillion highlights an innovative approach that emphasizes high-quality pharmaceutical production, aiming to meet the urgent needs for equitable access to advanced RNA therapies.
Conclusion:
The installation of the Biofoundry-in-a-Box represents a promising advancement in the realm of RNA therapeutics, reflecting Quotient Sciences’ commitment to expediting drug development. By combining novel manufacturing technologies with flexible production capabilities, this initiative not only aims to enhance the speed of bringing new RNA-based therapies to market but also underscores the potential for transformative changes in biopharmaceutical manufacturing practices.
