Introduction:
Biopharmaceutical company Merck has agreed to acquire Harpoon Therapeutics, a T-cell engager firm, for $680 million. This acquisition will expand Merck’s oncology pipeline and enhance its capabilities in immuno-oncology.
- The acquisition of Harpoon Therapeutics will give Merck access to its proprietary Tri-specific T-cell Activating Construct (TriTAC) platform, which has the potential to target multiple tumor types.
- Harpoon Therapeutics currently has two TriTAC molecules in clinical trials, HPN424 for the treatment of prostate cancer and HPN536 for the treatment of ovarian cancer.
- The acquisition will also include a preclinical program targeting mesothelin, a protein found on the surface of certain tumor cells.
- The deal is expected to close in the first half of 2021, subject to regulatory approval.
- This acquisition aligns with Merck’s strategy of investing in innovative technologies and platforms to advance its oncology portfolio.
Conclusion:
Merck’s acquisition of Harpoon Therapeutics will strengthen its position in the field of immuno-oncology by adding new capabilities and expanding its pipeline. The TriTAC platform has the potential to target multiple tumor types, offering new opportunities for cancer treatment. This acquisition demonstrates Merck’s commitment to investing in innovative technologies to drive advancements in oncology research and development.