Introduction:
Process developers in advanced therapy manufacturing should consider the logistics of shipping from the early stages of process development, according to Andrea Zobel, PhD, senior director at World Courier. Zobel spoke at Terrapinn’s Advanced Therapy Conference and emphasized the importance of considering shipping options, such as fresh versus frozen cells, storage temperatures, and the use of stabilization, in order to widen the options for distribution.
- Decisions about shipping are often made early on in the process, but the logistics of shipping should be considered throughout the entire development process.
- Choosing the final formulation, such as vials versus infusion bags, should be done in consultation with a shipper to avoid issues with storage and transportation.
- Considerations should be made for fresh versus frozen cells, storage temperatures, and the use of stabilization to expand distribution options.
- Companies should also consider decentralized manufacturing and whether to site their process within a hospital to further optimize shipping logistics.
- Equipment used in manufacturing should be compatible with shipping requirements to ensure efficient and seamless transfer of products.
Conclusion:
Advanced therapy manufacturers should prioritize thinking about shipping logistics from the early stages of process development. Considering factors such as formulation, storage temperatures, and equipment compatibility can widen distribution options and improve the overall efficiency of shipping advanced therapies.
