Breakthrough Collaboration: Lonza AG and NeuroSense Join Forces to Revolutionize Neurodegeneration Research

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🔬 NeuroSense Therapeutics Ltd has entered into a collaboration with Lonza AG to advance theranostics in neurodegeneration.
🧪 The collaboration will focus on identifying exosome-based biomarkers for early diagnosis and treatment.
💡 NeuroSense’s lead candidate for ALS, Prime C, has shown promising results in Phase IIb studies.
🤝 The partnership will leverage Lonza’s expertise in extracellular vesicles to develop methods for measuring biomarkers. 🧠
📢 Breakthrough Collaboration: Lonza AG and NeuroSense Revolutionize Neurodegeneration Research

Introduction: Swiss company Lonza AG has entered into a research and development collaboration with NeuroSense Therapeutics Ltd to identify exosome-based biomarkers for neurodegenerative diseases.

Main points:

  1. NeuroSense Therapeutics has successfully reached the primary and secondary safety and efficacy endpoints in a Phase IIb study with its lead candidate for amyotrophic lateral sclerosis (ALS), called Prime C, which combines ciprofloxacin and celecoxib.
  2. The collaboration with Lonza AG aims to develop a method utilizing Neuron-Derived Exosomes (NDEs) to evaluate biological changes occurring in people with neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease.
  3. NDEs are small extracellular vesicles that encapsulate various molecules and can pass the blood-brain barrier, providing a noninvasive depiction of the physiological status of neurons in the brain.
  4. Lonza AG will provide its expertise in extracellular vesicles, while NeuroSense Therapeutics will contribute its experience in utilizing biomarkers in neurodegenerative diseases.
  5. The collaboration aims to advance early diagnosis and treatment in the field of neurodegeneration.

Conclusion:

The collaboration between Lonza AG and NeuroSense Therapeutics Ltd aims to develop a method utilizing Neuron-Derived Exosomes (NDEs) to evaluate biological changes in neurodegenerative diseases. By identifying exosome-based biomarkers, the collaboration seeks to advance early diagnosis and treatment options for diseases such as Alzheimer’s, Parkinson’s, and ALS.

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